Nutramedix, BARBERRY - Microbial Defense

ATOPIC DERMATITIS

Klövekorn, W., Tepe, A., & Danesch, U. (2007). A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis. International Journal of Clinical Pharmacology and Therapeutics, 45(11), 583-591. Full Article

PSORIASIS

Bernstein, S., Donsky, H., Gulliver, W., Hamilton, D., Nobel, S., & Norman, R. (2006). Treatment of mild to moderate psoriasis with Relieva, a Mahonia aquifolium extract—a double-blind, placebo-controlled study.American Journal of Therapeutics, 13(2), 121-126. Full Article

Wiesenauer, M., & Lüdtke, R. (1996). Mahonia aquifolium in patients with Psoriasis vulgaris—an intraindividual study. Phytomedicine, 3(3), 231-235. Full Article

ATOPIC DERMATITIS

Donsky, H., & Clarke, D. (2007). Relieva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis. American Journal of Therapeutics, 14(5), 442-446. Full Article

CANCER

Damjanović, A., Zdunić, G., Šavikin, K., Mandić, B., Jadranin, M., Matić, I. Z., & Stanojković, T. (2016). Evaluation of the anti-cancer potential of Mahonia aquifolium extracts via apoptosis and anti-angiogenesis.Bangladesh J Pharmacol, 11, 741-749. Full Article

Čerňáková, M., Košt'álová, D., Kettmann, V., Plodová, M., Tóth, J., & Dřímal, J. (2002). Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium. BMC complementary and alternative medicine, 2(1), 2. Full Article

ANTIOXIDANT

Coklar, H., & Akbulut, M. (2017). Anthocyanins and phenolic compounds of Mahonia aquifolium berries and their contributions to antioxidant activity. Journal of Functional Foods, 35, 166-174. Full Article

Pyrkosz-Biardzka, K., Kucharska, A. Z., Sokół-Łętowska, A., Strugała, P., & Gabrielska, J. (2014). A comprehensive study on antioxidant properties of crude extracts from fruits of Berberis vulgaris L., Cornus mas L. and Mahonia aquifolium Nutt. Polish Journal of Food and Nutrition Sciences, 64(2), 91-99. Full Article

Kumaraswamy, M. V., & Satish, S. (2008). Free radical scavenging activity and lipoxygenase inhibition of Woodfordia fructicosa Kurz and Betula utilis Wall. African Journal of Biotechnology, 7(12), 2013-2016. Full Article

Račková, L., Májeková, M., Košt’álová, D., & Štefek, M. (2004). Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium. Structural Aspects. Bioorganic & Medicinal Chemistry, 12(17), 4709-4715. Full Article

Müller, K., & Ziereis, K. (1994). The antipsoriatic Mahonia aquifolium and its active constituents; I. Pro-and antioxidant properties and inhibition of 5-lipoxygenase. Planta Medica, 60(05), 421-424. Full Abstract

ANTIFUNGAL

Volleková, A., Košt'álová, D., Kettmann, V., & Tóth, J. (2003). Antifungal activity of Mahonia aquifolium extract and its major protoberberine alkaloids. Phytotherapy Research, 17(7), 834-837. Full Article

ANTI-INFLAMMATORY

Andreicuţ, A. D., Parvu, A. E., Moț, A. C., Parvu, M., FISCHER-FODOR, E. V. A., VASILE FELDRIHAN, A. F., ... & IRIMIE, A. (2018). Anti-inflammatory and antioxidant effects of Mahonia aquifolium leaves and bark extracts. Farmacia, 66(1). Full Article

ANTIMUTAGENIC ACTIVITY

Čerňáková, M., Košt'álová, D., Kettmann, V., Plodová, M., Tóth, J., & Dřímal, J. (2002). Potential antimutagenic activity of berberine, a constituent of Mahonia aquifolium. BMC Complementary and Alternative Medicine, 2(1), 2. Full Article

ANTIMICROBIAL

Rohrer, U., Kunz, E. M., Lenkeit, K., Schaffner, W., & Meyer, J. (2007). Antimicrobial activity of Mahonia aquifolium and two of its alkaloids against oral bacteria. Schweizer Monatsschrift fur Zahnmedizin= Revue mensuelle suisse d'odonto-stomatologie= Rivista mensile svizzera di odontologia e stomatologia, 117(11), 1126-1131. Full Abstract

Slobodníková, L., KoSt'álová, D., Labudová, D., Kotulová, D., & Kettmann, V. (2004). Antimicrobial activity of Mahonia aquifolium crude extract and its major isolated alkaloids. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 18(8), 674-676. Full Article

ANTITUSSIVE

Kardošová, A., Malovı́ková, A., Pätoprstý, V., Nosal'Ova, G., & Matáková, T. (2002). Structural characterization and antitussive activity of a glucuronoxylan from Mahonia aquifolium (Pursh) Nutt. Carbohydrate Polymers, 47(1), 27-33. Full Article

IMMUNOMODULATING

Galle, K., Müller-Jakic, B., Proebstle, A., Jurcic, K., Bladt, S., & Wagner, H. (1994). Analytical and pharmacological studies on Mahonia aquifolium. Phytomedicine, 1(1), 59-62. Full Article

"Once I turned 21, I was crippled by chronic sinusitis.  7 years of my life were spent sick, on antibiotics and steroids.  Barberry changed all that and wiped out my sinus infections and I'm now healthy and living my life to the fullest!"-M.Z.

“I don't know what you do to this herb but it's the best barberry I've ever seen. If anyone wants barberry I say don't waste your money on any other brand. I promise you they're not as good. I know. I tried them all.” – M.S

“This has been a great extract to use for P.A.N.D.A.S and it has lessened the severity of my daughter's tics.” – P.N

"Barberry helped me with getting over a urinary tract infection.  It lasted almost 2 months.  The meds that the doctor gave me didn't work, but after one full day of Barberry, it was GONE. " -O.M.

15 to 30 drops in 4 oz. of water 30 minutes before a meal twice daily.

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Barberry did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary.